72-year-old patient with dark spot on the back after sun exposure.Tchernev G, Semkova K, Nenoff P, Ananiev J, Geilen CC. Dtsch Med Wochenschr. 2013 Jun;138(25-26):1353-4.
Angiolymphoid hyperplasia with eosinophilia–an incidental finding after surgical excision. Tchernev G, Taneva T, Ananiev J, Cardoso JC, Gulubova M, Velev V, Karashmalakov A, Zisova L, Geilen CC. Wien Med Wochenschr. 2012 Oct;162(19-20):448-51.
New caspase-independent but ROS-dependent apoptosis pathways are targeted in melanoma cells by an iron-containing cytosine analogue.Franke JC, Plötz M, Prokop A, Geilen CC, Schmalz HG, Eberle J.Biochem Pharmacol. 2010 Feb 15;79(4):575-86.
Response of carcinoma in situ (actinic keratosis) to green tea concentrate plus capsicum. Morré DJ, Geilen CC, Welch AM, Morré DM. J Diet Suppl. 2009;6(4):385-9.
Hepoxilin A3 (HXA3) synthase deficiency is causative of a novel ichthyosis form. Nigam S, Zafiriou MP, Deva R, Kerstin N, Geilen C, Ciccoli R, Sczepanski M, Lohse M.FEBS Lett. 2008 Jan 23;582(2):279-85.
Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4. Kurbanov BM, Fecker LF, Geilen CC, Sterry W, Eberle J. Oncogene. 2007 May 17;26(23):3364-77.
Three coexisting lymphomas in one patient: genetically related or only a coincidence? Steinhoff M, Assaf C, Anagnostopoulos I, Geilen CC, Stein H, Hummel M. J Clin Pathol. 2006 Dec;59(12):1312-5.
Wegener’s granulomatosis presenting with granulomatous facial erythematous papules and plaques mimicking granulomatous rosacea.Steinhoff M, Steinhoff-Georgieva J, Geilen CC, Assaf C. Br J Dermatol. 2006 Jul;155(1):221-2.
Trastuzumab-induced cytoplasmic anti-neutrophilic cytoplasmic antibody necrotizing granulomatous panniculitis. Kalayciyan A, Makosz T, Assaf C, Geilen CC, Orfanos CE. J Am Acad Dermatol. 2006 May;54(5 Suppl):S249-51.
Loss of proapoptotic Bcl-2-related multidomain proteins in primary melanomas is associated with poor prognosis. Fecker LF, Geilen CC, Tchernev G, Trefzer U, Assaf C, Kurbanov BM, Schwarz C, Daniel PT, Eberle J. J Invest Dermatol. 2006 Jun;126(6):1366-71.
Malignant melanoma–markers for progression and prognosis in malignant melanoma. Geilen CC, Georgieva J, Milling A, Farthmann B. Front Radiat Ther Oncol. 2006;39:120-6.
Pathogenesis and clinical manifestation of Kaposi’s sarcoma. Geilen CC, Husak R, Steinhoff M. Front Radiat Ther Oncol. 2006;39:59-67.
Efficient TRAIL-R1/DR4-mediated apoptosis in melanoma cells by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Kurbanov BM, Geilen CC, Fecker LF, Orfanos CE, Eberle J. J Invest Dermatol. 2005 Nov;125(5):1010-9.
A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain. Hossini AM, Geilen CC, Fecker LF, Daniel PT, Eberle J. Oncogene. 2006 Apr 6;25(15):2160-9.
Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik. Oppermann M, Geilen CC, Fecker LF, Gillissen B, Daniel PT, Eberle J. Oncogene. 2005 Nov 10;24(49):7369-80.
Selective induction of apoptosis in melanoma cells by tyrosinase promoter-controlled CD95 ligand overexpression. Fecker LF, Geilen CC, Hossini AM, Schwarz C, Fechner H, Bartlett DL, Orfanos CE, Eberle J. J Invest Dermatol. 2005 Jan;124(1):221-8.
Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression. Bektas M, Jolly PS, Müller C, Eberle J, Spiegel S, Geilen CC. Oncogene. 2005 Jan 6;24(1):178-87.
Transition of Sézary syndrome into mycosis fungoides after complete clinical and molecular remission under extracorporeal photophoresis. Assaf C, Hummel M, Zemlin M, Steinhoff M, Geilen CC, Stein H, Orfanos CE. J Clin Pathol. 2004 Dec;57(12):1325-8.
Early TCR-beta and TCR-gamma PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications. Assaf C, Hummel M, Steinhoff M, Geilen CC, Orawa H, Stein H, Orfanos CE. Blood. 2005 Jan 15;105(2):503-10.
Detection of malignant melanoma in a giant congenital naevocytic naevus by positron emission tomography. Makosz T, Assaf C, Georgieva J, Orfanos CE, Geilen CC. Br J Dermatol. 2004 Sep;151(3):724-6.
Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells. Forsea AM, Müller C, Riebeling C, Orfanos CE, Geilen CC. Br J Cancer. 2004 Aug 16;91(4):803-10.
Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB. Schmelz K, Wieder T, Tamm I, Müller A, Essmann F, Geilen CC, Schulze-Osthoff K, Dörken B, Daniel PT. Oncogene. 2004 Sep 2;23(40):6743-59.
Death receptor-independent apoptosis in malignant melanoma induced by the small-molecule immune response modifier imiquimod. Schön MP, Wienrich BG, Drewniok C, Bong AB, Eberle J, Geilen CC, Gollnick H, Schön M. J Invest Dermatol. 2004 May;122(5):1266-76.
Dacarbazine but not temozolomide induces phototoxic dermatitis in patients with malignant melanoma. Treudler R, Georgieva J, Geilen CC, Orfanos CE. J Am Acad Dermatol. 2004 May;50(5):783-5.
Churg-Strauss syndrome: successful treatment with mycophenolate mofetil. Assaf C, Mewis G, Orfanos CE, Geilen CC. Br J Dermatol. 2004 Mar;150(3):598-600.
Differential involvement of ceramide in TNFalpha-mediated activation of NF-kappaB in primary human keratinocytes and HaCaT keratinocytes. Müller C, Bektas M, Geilen CC. Cell Mol Biol (Noisy-le-grand). 2003;49
Cutaneous T cell lymphoma and classic Hodgkin lymphoma of the B cell type within a single lymph node: composite lymphoma. Steinhoff M, Hummel M, Assaf C, Anagnostopoulos I, Treudler R, Geilen CC, Stein H, Orfanos CE. J Clin Pathol. 2004 Mar;57(3):329-31.
Regulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle. Kamp H, Geilen CC, Sommer C, Blume-Peytavi U. Exp Dermatol. 2003 Oct;12(5):662-72.
Verrucous carcinoma of the axilla: case report and review. Assaf C, Steinhoff M, Petrov I, Geilen CC, de Villiers EM, Schultz-Ehrenburg U, Orfanos CE. J Cutan Pathol. 2004 Feb;31(2):199-204.
Bodybuilder oleoma. Georgieva J, Assaf C, Steinhoff M, Treudler R, Orfanos CE, Geilen CC. Br J Dermatol. 2003 Dec;149(6):1289-90.
CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants. Eberle J, Fecker LF, Hossini AM, Wieder T, Daniel PT, Orfanos CE, Geilen CC. Oncogene. 2003 Dec 11;22(57):9131-41.
Expression and regulation of phospholipase D isoenzymes in human melanoma cells and primary melanocytes. Riebeling C, Müller C, Geilen CC. Melanoma Res. 2003 Dec;13(6):555-62.
Atypical generalized eruptive histiocytosis associated with acute monocytic leukemia. Klemke CD, Dippel E, Geilen CC, Koenigsmann MP, Thiel E, Orfanos CE, Goerdt S. J Am Acad Dermatol. 2003 Nov;49(5 Suppl):S233-6.
Conditional expression of exogenous Bcl-X(S) triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts. Hossini AM, Eberle J, Fecker LF, Orfanos CE, Geilen CC. FEBS Lett. 2003 Oct 23;553(3):250-6.
Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod. Schön M, Bong AB, Drewniok C, Herz J, Geilen CC, Reifenberger J, Benninghoff B, Slade HB, Gollnick H, Schön MP. J Natl Cancer Inst. 2003 Aug 6;95(15):1138-49.
Common clonal T-cell origin in a patient with T-prolymphocytic leukaemia and associated cutaneous T-cell lymphomas. Assaf C, Hummel M, Dippel E, Schwartz S, Geilen CC, Harder L, Siebert R, Steinhoff M, Klemke CD, Thiel E, Goerdt S, Stein H, Orfanos CE. Br J Haematol. 2003 Feb;120(3):488-91.
Standard and innovative therapy of psoriasis. Geilen CC, Orfanos CE. Clin Exp Rheumatol. 2002 Nov-Dec;20(6 Suppl 28):S81-7.
Interleukin-4 induces apoptosis in cultured human follicular keratinocytes, but not in dermal papilla cells. Mandt N, Geilen CC, Wrobel A, Gelber A, Kamp H, Orfanos CE, Blume-Peytavi U. Eur J Dermatol. 2002 Sep-Oct;12(5):432-8.
The role of nuclear factor-kappa B and melanogenesis in tumor necrosis factor-alpha-induced apoptosis of normal human melanocytes. Shang J, Eberle J, Geilen CC, Hossini AM, Fecker LF, Orfanos CE, Tebbe B. Skin Pharmacol Appl Skin Physiol. 2002 Sep-Oct;15(5):321-9.
Endothelin-1 decreases basic apoptotic rates in human melanoma cell lines. Eberle J, Fecker LF, Orfanos CE, Geilen CC. J Invest Dermatol. 2002 Sep;119(3):549-55.
The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. Riebeling C, Forsea AM, Raisova M, Orfanos CE, Geilen CC. Br J Cancer. 2002 Jul 29;87(3):366-71.
Magnetic bead RT-PCR: establishment of a new method for detecting circulating melanoma cells. Georgieva J, Milling A, Orfanos CE, Geilen CC. Melanoma Res. 2002 Aug;12(4):309-17.
Decreased proliferation of human melanoma cell lines caused by antisense RNA against translation factor eIF-4A1. Eberle J, Fecker LF, Bittner JU, Orfanos CE, Geilen CC. Br J Cancer. 2002 Jun 17;86(12):1957-62.
Inducible nitric oxide synthase is expressed in normal human melanocytes but not in melanoma cells in response to tumor necrosis factor-alpha, interferon-gamma, and lipopolysaccharide. Fecker LF, Eberle J, Orfanos CE, Geilen CC. J Invest Dermatol. 2002 Jun;118(6):1019-25.
Cutaneous mastocytosis. Assaf C, Geilen CC, Tebbe B, Schulze K, Orfanos CE. Lancet. 2002 Apr 27;359(9316):1465.
Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes. Raisova M, Goltz G, Bektas M, Bielawska A, Riebeling C, Hossini AM, Eberle J, Hannun YA, Orfanos CE, Geilen CC. FEBS Lett. 2002 Apr 10;516(1-3):47-52.
Buschke-Ollendorff syndrome–differential diagnosis of disseminated connective tissue lesions. Assmann A, Mandt N, Geilen CC, Blume-Peytavi U. Eur J Dermatol. 2001 Nov-Dec;11(6):576-9.
Sphingolipid signaling in epidermal homeostasis. Current knowledge and new therapeutic approaches in dermatology. Geilen CC, Barz S, Bektas M. Skin Pharmacol Appl Skin Physiol. 2001 Sep-Oct;14(5):261-71.
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis. Raisova M, Hossini AM, Eberle J, Riebeling C, Wieder T, Sturm I, Daniel PT, Orfanos CE, Geilen CC. J Invest Dermatol. 2001 Aug;117(2):333-40.
Growth and characterization of a cell line from a human primary neuroendocrine carcinoma of the skin (Merkel cell carcinoma) in culture and as xenograft. Krasagakis K, Almond-Roesler B, Geilen C, Fimmel S, Krengel S, Chatzaki E, Gravanis A, Orfanos CE. J Cell Physiol. 2001 Jun;187(3):386-91.
Mycophenolate mofetil as a systemic antipsoriatic agent: positive experience in 11 patients. Geilen CC, Arnold M, Orfanos CE. Br J Dermatol. 2001 Mar;144(3):583-6.
Nodular and bullous cutaneous mastocytosis of the xanthelasmoid type: case report. Husak R, Blume-Peytavi U, Pfrommer C, Geilen CC, Goerdt S, Orfanos CE. Br J Dermatol. 2001 Feb;144(2):355-8.
Matting of hair: a multifactorial enigma. Al Ghani MA, Geilen CC, Blume-Peytavi U, Orfanos CE. Dermatology. 2000;201(2):101-4.
Bcl-2 transfected HaCaT keratinocytes resist apoptotic signals of ceramides, tumor necrosis factor alpha and 1 alpha, 25-dihydroxyvitamin D(3). Müller-Wieprecht V, Riebeling C, Stooss A, Orfanos CE, Geilen CC. Arch Dermatol Res. 2000 Sep;292(9):455-62.
Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release. Raisova M, Bektas M, Wieder T, Daniel P, Eberle J, Orfanos CE, Geilen CC. FEBS Lett. 2000 May 4;473(1):27-32.
Lack of efficacy of topical mycophenolic acid in psoriasis vulgarism. Geilen CC, Mrowietz U. J. Am Acad Dermatol. 2000 May;42(5 Pt 1):837-40.
Structure-dependent effects of glucose-containing analogs of platelet activating factor (PAF) on membrane integrity. Wiese A, Wieder T, Mickeleit M, Reinöhl S, Geilen CC, Seydel U, Reutter W. Biol Chem. 2000 Feb;381(2):135-44.
Mycophenolate mofetil: a new immunosuppressive drug in dermatology and its possible uses. Geilen CC, Orfanos-Boeckel H, Offermann G, Orfanos CE. Hautarzt. 2000 Feb;51(2):63-9.
Multiple familial cutaneous glomangioma: a pedigree of 4 generations and critical analysis of histologic and genetic differences of glomus tumors. Blume-Peytavi U, Adler YD, Geilen CC, Ahmad W, Christiano A, Goerdt S, Orfanos CE. J Am Acad Dermatol. 2000 Apr;42(4):633-9.
Different vitamin D analogues induce sphingomyelin hydrolysis and apoptosis in the human keratinocyte cell line HaCaT. Bektas M, Orfanos CE, Geilen CC. Cell Mol Biol (Noisy-le-grand). 2000 Feb;46(1):111-9.
Frequent presence of Helicobacter pylori infection in chronic urticaria. Radenhausen M, Schulzke JD, Geilen CC, Mansmann U, Treudler R, Bojarski C, Orfanos CE, Tebbe B. Acta Derm Venereol. 2000 Jan-Feb;80(1):48-9.
Mechanisms of action of phospholipid analogs as anticancer compounds. Wieder T, Reutter W, Orfanos CE, Geilen CC. Prog Lipid Res. 1999 May;38(3):249-59.
Unilateral angiolymphoid hyperplasia with eosinophilia involving the left arm and hand. Arnold M, Geilen CC, Coupland SE, Krengel S, Dippel E, Spröder J, Goerdt S, Orfanos CE. J Cutan Pathol. 1999 Oct;26(9):436-40.
Kaposi’s sarcoma is an important risk factor for survival in HIV-infected patients independent of CD4+ cell count. Husak R, Mansmann U, Wölfer LU, Geilen CC, Goerdt S, Orfanos CE. AIDS. 1999 Feb 25;13(3):432-3.
Induction of apoptosis by synthetic ceramide analogues in the human keratinocyte cell line HaCaT. Bektas M, Dullin Y, Wieder T, Kolter T, Sandhoff K, Brossmer R, Ihrig P, Orfanos CE, Geilen CC. Exp Dermatol. 1998 Dec;7(6):342-9.
Successful treatment of erythrodermic psoriasis with mycophenolate mofetil. Geilen CC, Tebbe B, Garcia Bartels C, Krengel S, Orfanos CE. Br J Dermatol. 1998 Jun;138(6):1101-2..
Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine. Wieder T, Orfanos CE, Geilen CC. J Biol Chem. 1998 May 1;273(18):11025-31.
Expression and regulation of phospholipase D in the human keratinocyte cell line HaCaT. Müller-Wieprecht V, Riebeling C, Alexander C, Scholz FR, Höer A, Wieder T, Orfanos CE, Geilen CC. FEBS Lett. 1998 Mar 27;425(2):199-203.
Ceramide signalling: regulatory role in cell proliferation, differentiation and apoptosis in human epidermis. Geilen CC, Wieder T, Orfanos CE. Arch Dermatol Res. 1997 Sep;289(10):559-66.
Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues. Wieder T, Geilen CC, Kolter T, Sadeghlar F, Sandhoff K, Brossmer R, Ihrig P, Perry D, Orfanos CE, Hannun YA. FEBS Lett. 1997 Jul 14;411(2-3):260-4.
1alpha,25-dihydroxyvitamin D3 induces sphingomyelin hydrolysis in HaCaT cells via tumor necrosis factor alpha. Geilen CC, Bektas M, Wieder T, Kodelja V, Goerdt S, Orfanos CE. J Biol Chem. 1997 Apr 4;272(14):8997-9001.
Current use and future potential role of retinoids in dermatology. Orfanos CE, Zouboulis CC, Almond-Roesler B, Geilen CC. Drugs. 1997 Mar;53(3):358-88.
L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-1alpha and IL-6 in cultured human keratinocytes in vitro. Tebbe B, Wu S, Geilen CC, Eberle J, Kodelja V, Orfanos CE. J Invest Dermatol. 1997 Mar;108(3):302-6.
Superior vena cava syndrome. Description of 3 cases and review of the literature. Goerdt S, Krengel S, Tenorio S, Tebbe B, Geilen C, Orfanos CE. Hautarzt. 1997 Feb;48(2):122-6.
The phospholipid analogue hexadecylphosphocholine (HePC) inhibits proliferation of keloid fibroblasts in vitro and modulates their fibronectin and integrin synthesis. Blume-Peytavi U, Geilen CC, Sommer C, Almond-Roesler B, Orfanos CE. Arch Dermatol Res. 1997 Feb;289(3):164-9.
Inhibition of plasma membrane NADH oxidase activity and growth of HeLa cells by natural and synthetic retinoids. Dai S, Morré DJ, Geilen CC, Almond-Roesler B, Orfanos CE, Morré DM. Mol Cell Biochem. 1997 Jan;166(1-2):101-9.
Cell-matrix interactions of normal and transformed human keratinocytes in vitro are modulated by the synthetic phospholipid analogue hexadecylphosphocholine. Schön M, Schön MP, Geilen CC, Hoffmann M, Hakyi N, Orfanos CE, Reutter W. Br J Dermatol. 1996 Nov;135(5):696-703.
Capsaicin inhibits plasma membrane NADH oxidase and growth of human and mouse melanoma lines. Morré DJ, Sun E, Geilen C, Wu LY, de Cabo R, Krasagakis K, Orfanos CE, Morré DM. Eur J Cancer. 1996 Oct;32A(11):1995-2003.
The mitogen-activated protein kinases system (MAP kinase cascade): its role in skin signal transduction. A review. Geilen CC, Wieprecht M, Orfanos CE. J Dermatol Sci. 1996 Sep;12(3):255-62.
Detection of Helicobacter pylori in dermatoses. Clinical incidental finding or pathogenetic association?. Tebbe B, Geilen CC, Orfanos CE. Hautarzt. 1996 Aug;47(8):587-90.
Evidence for phosphorylation of CTP:phosphocholine cytidylyltransferase by multiple proline-directed protein kinases. Wieprecht M, Wieder T, Paul C, Geilen CC, Orfanos CE. J Biol Chem. 1996 Apr 26;271(17):9955-61.
Helicobacter pylori infection and chronic urticaria. Tebbe B, Geilen CC, Schulzke JD, Bojarski C, Radenhausen M, Orfanos CE. J Am Acad Dermatol. 1996 Apr;34(4):685-6.
Determination of cytidine 5′-monophospho-N-acetylneuraminic acid pool size in cell culture scale using high-performance anion-exchange chromatography with pulsed amperometric detection. Fritsch M, Geilen CC, Reutter W. J Chromatogr A. 1996 Mar 15;727(2):223-30.
The antitumor phospholipid analog, hexadecylphosphocholine, activates cellular phospholipase D. Wieder T, Zhang Z, Geilen CC, Orfanos CE, Giuliano AE, Cabot MC. Cancer Lett. 1996 Feb 27;100(1-2):71-9.
c-Ha-ras oncogene expression increases choline uptake, CTP: phosphocholine cytidylyltransferase activity and phosphatidylcholine biosynthesis in the immortalized human keratinocyte cell line HaCaT. Geilen CC, Wieder T, Boremski S, Wieprecht M, Orfanos CE. Biochim Biophys Acta. 1996 Feb 16;1299(3):299-305.
Clinical fluconazole and itraconazole resistance of oro-gastrointestinal candidiasis in a patient with AIDS. Tebbe B, Boyvat A, Geilen CC, Wölfer LU, Seibold M, Orfanos CE. Hautarzt. 1996 Feb;47(2):136-9.
The vitamin D3 analogue, calcipotriol, induces sphingomyelin hydrolysis in human keratinocytes. Geilen CC, Bektas M, Wieder T, Orfanos CE. FEBS Lett. 1996 Jan 2;378(1):88-92.
Phosphatidylcholine biosynthesis as a target for phospholipid analogues. Geilen CC, Wieder T, Orfanos CE. Adv Exp Med Biol. 1996;416:333-6.
Influence of extracellular matrices on ganglioside pattern of two hepatoma cell lines with different adhesive properties. Fritsch M, Geilen CC, Heidrich C, Reutter W. FEBS Lett. 1995 Dec 4;376(3):159-63.
Two new sphingomyelin analogues inhibit phosphatidylcholine biosynthesis by decreasing membrane-bound CTP: phosphocholine cytidylyltransferase levels in HaCaT cells. Wieder T, Perlitz C, Wieprecht M, Huang RT, Geilen CC, Orfanos CE. Biochem J. 1995 Nov 1;311 ( Pt 3):873-9.
The effect of two synthetic phospholipids on cell proliferation and phosphatidylcholine biosynthesis in Madin-Darby canine kidney cells. Wieder T, Haase A, Geilen CC, Orfanos CE. Lipids. 1995 May;30(5):389-93. Erratum in: Lipids 1995 Jul;30(7):681.
Growth factors stimulate phosphorylation of CTP:phosphocholine cytidylyltransferase in HeLa cells. Wieprecht M, Wieder T, Geilen CC, Orfanos CE. FEBS Lett. 1994 Oct 17;353(2):221-4.
Identification of a putative membrane-interacting domain of CTP:phosphocholine cytidylyltransferase from rat liver. Wieder T, Geilen CC, Wieprecht M, Becker A, Orfanos CE. FEBS Lett. 1994 May 30;345(2-3):207-10.
Phospholipid analogue hexadecylphosphocholine inhibits proliferation and phosphatidylcholine biosynthesis of human epidermal keratinocytes in vitro. Detmar M, Geilen CC, Wieder T, Orfanos CE, Reutter W. J Invest Dermatol. 1994 Apr;102(4):490-4.
Phospholipid analogues: side chain- and polar head group-dependent effects on phosphatidylcholine biosynthesis. Geilen CC, Haase A, Wieder T, Arndt D, Zeisig R, Reutter W. J Lipid Res. 1994 Apr;35(4):625-32.
Uptake, subcellular distribution and metabolism of the phospholipid analogue hexadecylphosphocholine in MDCK cells. Geilen CC, Wieder T, Haase A, Reutter W, Morré DM, Morré DJ. Biochim Biophys Acta. 1994 Feb 10;1211(1):14-22.
Determination of alkylphosphocholines by high-performance liquid chromatography with light-scattering mass detection. Wieder T, Fritsch M, Haase A, Geilen CC. J Chromatogr. 1994 Jan 14;652(1):9-13.
N-[2-bromocinnamyl(amino)ethyl]-5-isoquinolinesulphonamide (H-89) inhibits incorporation of choline into phosphatidylcholine via inhibition of choline kinase and has no effect on the phosphorylation of CTP:phosphocholine cytidylyltransferase. Wieprecht M, Wieder T, Geilen CC. Biochem J. 1994 Jan 1;297 ( Pt 1):241-7.
Comparative study of high-mannose-type oligosaccharides in membrane glycoproteins of rat hepatocytes and different rat hepatoma cell lines. Nuck R, Paul C, Wieland B, Heidrich C, Geilen CC, Reutter W. Eur J Biochem. 1993 Aug 15;216(1):215-21.
Synthesis of 2-deoxy-D-galactose containing gangliosides in vivo. Hwang YH, Kohla G, Geilen CC, Paul C, Kannicht C, Grunow D, Pohlentz G, Egge H, Nuck R, Reutter W. FEBS Lett. 1993 Jul 19;327(1):63-7.
NADH oxidase activity of rat liver plasma membrane activated by guanine nucleotides. Morré DJ, Davidson M, Geilen C, Lawrence J, Flesher G, Crowe R, Crane FL. Biochem J. 1993 Jun 15;292 ( Pt 3):647-53.
Antagonism of phorbol-ester-stimulated phosphatidylcholine biosynthesis by the phospholipid analogue hexadecylphosphocholine. Wieder T, Geilen CC, Reutter W. Biochem J. 1993 Apr 15;291 ( Pt 2):561-7.
A selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-bromocinnamyl(amino)ethyl]-5-isoquinolinesulfonamide (H-89), inhibits phosphatidylcholine biosynthesis in HeLa cells. Geilen CC, Wieprecht M, Wieder T, Reutter W. FEBS Lett. 1992 Sep 14;309(3):381-4.
Incorporation of the hexose analogue 2-deoxy-D-galactose into membrane glycoproteins in HepG2 cells. Geilen CC, Kannicht C, Orthen B, Heidrich C, Paul C, Grunow D, Nuck R, Reutter W. Arch Biochem Biophys. 1992 Jul;296(1):108-14.
Incorporation of N-acyl-2-amino-2-deoxy-hexoses into glycosphingolipids of the pheochromocytoma cell line PC 12. Kayser H, Geilen CC, Paul C, Zeitler R, Reutter W. FEBS Lett. 1992 Apr 20;301(2):137-40.
Hexadecylphosphocholine inhibits translocation of CTP:choline-phosphate cytidylyltransferase in Madin-Darby canine kidney cells. Geilen CC, Wieder T, Reutter W. J Biol Chem. 1992 Apr 5;267(10):6719-24.
2-Deoxy-2-fluoro-D-galactose protein N-glycosylation. Loch N, Geilen CC, Spörndle I, Oberdorfer F, Keppler D, Tauber R, Reutter W. FEBS Lett. 1991 Dec 9;294(3):217-20.
The phospholipid analogue hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis in Madin-Darby canine kidney cells. Haase R, Wieder T, Geilen CC, Reutter W. FEBS Lett. 1991 Aug 19;288(1-2):129-32.
The phospholipid analogue, hexadecylphosphocholine, inhibits protein kinase C in vitro and antagonises phorbol ester-stimulated cell proliferation. Geilen CC, Haase R, Buchner K, Wieder T, Hucho F, Reutter W. Eur J Cancer. 1991;27(12):1650-3.